Home  >  Products  >  Chk2 (Checkpoint Kinase 2, Chek 2, Chek2, Chk 2, CDS 1, CDS1, HuCds 1, HuCds1, LFS2, PP1425, RAD 53, RAD53, Serine/threonine Protein Kinase Chk2)
Chk2 (Checkpoint Kinase 2, Chek 2, Chek2, Chk 2, CDS 1, CDS1, HuCds 1, HuCds1, LFS2, PP1425, RAD 53, RAD53, Serine/threonine Protein Kinase Chk2)

Chk2 (Checkpoint Kinase 2, Chek 2, Chek2, Chk 2, CDS 1, CDS1, HuCds 1, HuCds1, LFS2, PP1425, RAD 53, RAD53, Serine/threonine Protein Kinase Chk2)

Cat no: C4200-90M

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
Checkpoint homolog CHK2 is an important cell cycle checkpoint regulator. The protein is rapidly activated by phosphorylation in response to DNA damage and to replication block. When activated, CHK2 is known to prevent entry into mitosis and has been shown to regulate the tumor suppressor protein p53, leading to cell cycle arrest in G1. At least 12 isoforms are produced by alternative splicing. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.75ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C4200-90M
Reactivities: Human, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% Thimerosal, 0.05% sodium azide. Reconstitute with 100ul of sterile dH2O.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: Checkpoint-like protein CHK2, CHK2 Checkpoint Homolog (S. pombe), EC=2.7.11.1, RP11-436C9.1
Additional info: Recognizes human Checkpoint homolog CHK2 at 61kD. Species Crossreactivity: rat. Sequence Homology: mouse

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave