Chlamydia Trachomatis, Human, IgG, BioAssay(TM) ELISA Kit

The United States Biological Chlamydia Trachomatis, Human, IgG, BioAssay(TM) ELISA Kit is intended for use in evaluating a sample's serologic status to Chlamydia trachomatis infection. It is also used to evaluate paired sera for the presence of a significant increase in specific IgG as indicative of a recent or current Chlamydia Trachomatis infection.\nChlamydia Trachomatis is one of the most common human pathogens. Of the 15 recognized serotypes, 4 (A, B, Ba, and C) have been shown to cause hyperendemic blinding trachoma, a disease which afflicts hundreds of millions of people in developing countries. Three serotypes (L-1, L-2, and L-3) are the causes of lymphogranuloma venereum (LGV), a sexually transmitted systemic disease. The other serotypes (D through K) have been associated with genital tract infections and sporadic cases of conjunctivitis in industrialized societies. These agents are the major recognized cause of nongonococcal urethritis in men, in whom they may also cause epididymitis. In women, C. trachomatis causes cervicitis and has been associated with acute salpingitis. Infants born through an infected birth canal may contract the infection and then develop inclusion conjunctivitis of the newborn and/or the characteristic chlamydial pneumonia syndrome. High levels of anti-Chlamydia IgG antibody are of value in the detection of chronic or systemic infections such as salpingitis, mechanical infertility, perihepatitis, epididymitis, Reiter's syndrome and pneumonitis. The United States Biological Chlamydia Trachomatis, Human, IgG, BioAssay(TM) ELISA Kit employs the LGV type 2 broadly reacting antigen of Chlamydia Trachomatis. It will detect Chlamydia Trachomatis, Chlamydia Psittaci and Chlamydia Pneumoniae (TWAR) antibodies.\n\nKit Components: \n1. Microtiter Plate: 1x96 wells\n2. Sample diluent: 1X22ml \n3. Wash Buffer,10X: 1X100ml \n4. Tetramethylbenzidine (TMB): 1x15ml\n5. Enzyme conjugate: 1X12 ml\n6. Cut-off Calibrator: 1X150ul \n7. Negative control: 1X150ul \n8. Positive control: 1X150ul\n9. Stop solution:1X12 ml (2 N HCl) \n\nStorage and Stability:\nStore all components at 4 degrees C. Stable for 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

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SPECIFICATIONS

Catalog Number

C4250-16

Size

1Kit

Applications

ELISA

Reactivities

Hum

References

1. Schachter, J. 1978. Chlamydial infections. N. Engl. J. Med. 298: 428-435, 490-495, 540-549. 2. Sarov, I., et al., Int. J. Fertil 31: 193- 197. 3. Kaneti, J. et al. (1988). IgG and IgA Antibodies specific for Chlymydia trachomatis in Acute Epididymitis. Europ. Urol. 14: 323-327. 4. Kletter, Y., et al., In: Proceedings of The European Society for Chlamydia Research, Societa Editrice Esculapio, Bologna. 1988. P. 170. 5. Paran, H., Heimer, D. and Sarov, I. (1986). Serological, Clinica and Radiological Findings in Adults with Bronchopulmonary Infections Caused by Chlamydia trachomatis. Isr. J. Med. Sci. 22: 823-827.