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Chloramphenicol

Chloramphenicol

Cat no: C4350

Supplier: United States Biological
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Chloramphenicol is a chlorine-containing antibiotic produced by Streptomyces venezuelae. It has a wide spectrum of activity against gram-positive and gram-negative cocci and bacilli (including anaerobes), Rickettsia, Mycoplasma, and Chlamydia. It inhibits prokaryotic protein synthesis by attaching to the 50S ribosomal subunit. This inhibits peptidyltransferase, thereby preventing the formation of peptide bonds. It also inhibits protein synthesis in mitochondria which accounts for its toxic effects that cause aplastic anemia. Chloramphenicol has other adverse effects such as bone marrow depression, and gray baby syndrome. It
Catalogue number: C4350
Size: 25g
Purity: 98.5-102%
Alternative names: Chloromycetin
References: US Biological application reference: Dennis, A.M. et al., (2010) Bioconjugate Chem. 21; 1160-1170.

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