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CHMP1A, Recombinant, Human, aa1-196, His-Tag (Charged Multivesicular Body Protein 1a, CHMP1, PCOLN3, PRSM1, VPS46-1, VPS46A)

Cat no: 138630

CHMP1A, Recombinant, Human, aa1-196, His-Tag (Charged Multivesicular Body Protein 1a, CHMP1, PCOLN3, PRSM1, VPS46-1, VPS46A)

Charged multivesicular body protein 1a, also known as CHMP1A, belongs to the vacuolar sorting protein family and functions as chromatin-modifying protein. These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), as well as required for the formation of these bodies. The MVBs pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. CHMP1 interacts with VPS4B and localizes to early endosomes. Two isoforms, encoded by distinct genes, exists for CHMP1. They are designated CHMP1A and CHMP1B. \n\nSource:\nRecombinant protein corresponding to aa1-196 from human CHMP1A at N-terminal, fused to His-tag expressed in E.coli. \n\nMolecular Weight: \n~24.1kD (219aa)\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGSMDDTLFQ LKFTAKQLEK LAKKAEKDSK AEQAKVKKAL LQKNVECARV YAENAIRKKN EGVNWLRMAS RVDAVASKVQ TAVTMKGVTK NMAQVTKALD KALSTMDLQK VSSVMDRFEQ QVQNLDVHTS VMEDSMSSAT TLTTPQEQVD SLIMQIAEEN GLEVLDQLSQ LPEGASAVGE SSVRSQEDQL SRRLAALRN\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

138630

Size

20ug

Form

Supplied as a liquid in 20mM tris-HCl buffer, pH 8.0, 0.1M sodium chloride, 1mM DTT, 20% glycerol.

Purity

~85% (SDS-PAGE)

References

1. Stauffer D R., et al. (2001) J Cell Sci. 114:2383-2393 2. Howard T L., et al. (2001) J Cell Sci. 114: 2395-2404.

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Applications

ELISA

Reactivities

Hum

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Applications

IF

Hosts

Mouse

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Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

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Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

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Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info
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