Home  >  Products  >  CHMP5 (Charged Multivesicular Body Protein 5, Chromatin-modifying Protein 5, SNF7 Domain-containing Protein 2, Vacuolar Protein Sorting-associated Protein 60, Vps60, hVps60, C9orf83, SNF7DC2, CGI-34, HSPC177, PNAS-2, PNAS-114)
CHMP5 (Charged Multivesicular Body Protein 5, Chromatin-modifying Protein 5, SNF7 Domain-containing Protein 2, Vacuolar Protein Sorting-associated Protein 60, Vps60, hVps60, C9orf83, SNF7DC2, CGI-34, HSPC177, PNAS-2, PNAS-114)

CHMP5 (Charged Multivesicular Body Protein 5, Chromatin-modifying Protein 5, SNF7 Domain-containing Protein 2, Vacuolar Protein Sorting-associated Protein 60, Vps60, hVps60, C9orf83, SNF7DC2, CGI-34, HSPC177, PNAS-2, PNAS-114)

Cat no: C5039-02B

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
CHMP5 is a component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. In case of infection, the HIV-1 virus takes advantage of the ESCRT-III complex for budding and exocytic cargoes of viral proteins. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1-3ug/ml Optimal dilutions to be determined by the researcher. Positive Control: K562 lysate Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C5039-02B
Reactivities: Human
Hosts: Goat
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Ward DM, Vaughn MB, Shiflett SL, White PL, Pollock AL, Hill J, Schnegelberger R, Sundquist WI, Kaplan J. The role of LIP5 and CHMP5 in multivesicular body formation and HIV-1 budding in mammalian cells. J Biol Chem. 2005 Mar 18;280(11):10548-55. Epub 2005 Jan 11.
Additional info: Recognizes human CHMP5.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave