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Cholecystokinin A Receptor (CCKA Receptor, CCKAR, AW106902)

Cholecystokinin A Receptor (CCKA Receptor, CCKAR, AW106902)

Cat no: C5042-20D

Supplier: United States Biological
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Gene ID: 886 Cholecystokinin A Receptor (CCKAR) is one of two 7TM receptors for cholecystokinin peptide hormones. This GPCR is involved in gallbladder contraction, insulin secretion, and central nervous system function. CCK-A R has been implicated in pancreatic tumorigenesis as well as the pathogenesis of eating disorders and drug addiction. Human CCK-A R shares 89% aa sequence identity with mouse and rat CCKAR. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry (paraffin-embedded sections). Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C5042-20D
Reactivities: Human
Hosts: Goat
Applications: ELISA, Immunohistochemistry, Western Blot
Size: 100ug
Form: Tris-saline [pH7.3] with 0.5% BSA
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: Beglinger C, Degen L, Matzinger D, D'Amato M, Drewe J. Loxiglumide, a CCK-A receptor antagonist, stimulates calorie intake and hunger feelings in humans. Am J Physiol Regul Integr Comp Physiol. 2001 Apr;280(4):R1149-54. PMID: 11247838 PMID: 15100163
Additional info: Recognizes human Cholecystokinin A Receptor (CCKA Receptor, CCKAR, AW106902). Species Crossreactivity: May recognize rat or mouse based on sequence homology.

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