CHRNA1 Antibody

Cat no: 251823

Supplier: ABBIOTEC

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Description
Additional Information

After binding acetylcholine, the acetylcholine receptor (CHRNA1) responds by an e, Xenopus/Amphibian,tensive change in conformation that affects all subunits and leads to the opening of an ion-conducting channel across the plasma membrane. CHRNA1 is a pentamer of two alpha chains, and one each of the beta, delta, and gamma (in immature muscle) or epsilon (in mature muscle) chains. The alpha subunit is the main focus for antibody binding in myasthenia gravis. Myasthenia gravis is characterized by sporadic muscular fatigability and weakness, occurring chiefly in muscles innervated by cranial nerves, and characteristically improved by cholinesterase-inhibiting drugs.

Catalogue number:	251823
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P02708
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CHRNA1.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Acetylcholine receptor subunit alpha; CHRNA1; ACHRA; CHNRA