Chronic Lymphoid Leukemia-PB-Mononuclear Cells are isolated from Chronic Lymphoid Leukemia-peripheral blood by diluting the blood with phosphate-buffered saline and using gradient separation. Mononuclear Cells can be processed to isolate subpopulations. Chronic Lymphoid Leukemia-PBone MarrowNC are available in untreated and relapsed/refractory stages.