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CIITA (Class II Trans Activator, C2TA, CIITA IV, MHC2TA, MHC class II transactivator)

Cat no: C5072-61A


Supplier: United States Biological
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Applications: Suitable for use in ELISA, Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Western Blotting: 1:1000-1:2000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C5072-61A
Reactivities: Human
Hosts: Rabbit
Applications: ELISA, Immunoprecipitation, Western Blot
Size: 100ug
Form: 0.15M Sodium Chloride, 0.02M Potassium Phosphate [pH 7.2] containing 0.01% sodium azide
P type: Pab
Isotype: IgG
Purity: Purified
Alternative names: C2TA, CIITA IV, MHC2TA, MHC class II transactivator
References: Harton JA et al. GTP binding by class II transactivator: role in nuclear import. Science 285:1402-5 (1999). Cressman DE et al. A defect in the nuclear translocation of CIITA causes a form of type II bare lymphocyte syndrome. Immunity 10:163-71 (1999). Steimle V et al. Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome). Cell 75:135-46 (1993).
Additional info: Detects human CIITA Species Crossreactivity: Crossreacts with Human.

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