Ciliary Neurotrophic Factor (CNTF)

Cat no: C5073-05G

Supplier: United States Biological

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Description
Additional Information

CNTF mainly signals through binding to a receptor complex consisting of a CNTFRa subunit, two beta components, gp130 and LIFR, resulting ultimately in the activation of JAK/STAT signalling pathway, but CNTF has also been shown to bind to the receptor for interleukin-6 (IL-6R). Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 0.5-2ug/ml Western Blot: 0.1-0.2ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Catalogue number:	C5073-05G
Reactivities:	Human
Hosts:	Rabbit
Applications:	ELISA, Western Blot
Size:	100ug
Form:	Supplied as a lyophilized powder from PBS, pH 7.2. No preservative added. Reconstitute with 100ul sterile 40-50% glycerol, ddH2O.
P type:	Pab
Isotype:	IgG
Purity:	Purified by immunoaffinity chromatography.
References:	1. Vergara, C. and Ramirez, B. (2004) CNTF, a pleiotropic cytokine: emphasis on its myotrophic role. Brain Res. Rev. 47: 161-173.
Additional info:	Recognizes human CNTF (ciliary neurotrophic factor).

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Ciliary Neurotrophic Factor (CNTF)

Cat no: C5073-05G

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