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Ciliobrevin A

Cat no: 006833


Supplier: United States Biological
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Ciliobrevin A is a Hedgehog pathway inhibitor; ciliogenesis inhibitor. The Hedgehog (HH) signaling pathway is targeted for anti-cancer therapeutics. Ciliobrevin A inhibited proliferation of cerebellar granula neuron precursor cells, an important model of HH signaling.
Catalogue number: 006833
Size: 10mg
Alternative names: 2,4-Dichloro-a-(3,4-dihydro-4-oxo-2(1H)-quinazolinylidene)-b-oxobenzenepropanenitrile; HPI-4;
References: Heald, R., et al.: Nature, 382, 420 (1996), Gaglio, T., et al.: J. Cell Biol., 138, 1055 (1997), Zhu, G., et al.: J. Med. Chem., 49, 2063 (2006), Varma, D., et al.: J. Cell Biol., 182, 1045 (2008),

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