CITED2 (Cbp/p300-interacting Transactivator 2, MSG-related Protein 1, MRG-1, P35srj, MRG1)

Cat no: C5675-06K

Supplier: United States Biological

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Cited 2 is a cAMP-responsive element-binding protein (CBP)/p300 interacting transcriptional modulator and a proposed negative regulator for hypoxia-inducible factor-1 alpha. Recruitment of CBP/p300 by HIF-1 is essential for the transcriptional response to hypoxia. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:4000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	C5675-06K
Hosts:	Goat
Applications:	ELISA
Size:	100ug
Form:	Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
P type:	Pab
Isotype:	IgG
Purity:	Purified by immunoaffinity chromatography.
References:	1. Weninger WJ, Floro KL, Bennett MB, Withington SL, Preis JI, Barbera JP, Mohun TJ, Dunwoodie SL. Cited2 is required both for heart morphogenesis and establishment of the left-right axis in mouse development. Development. 2005 Mar;132(6):1337-48. PMID: 15750185.
Additional info:	Recognizes CITED2. Species sequence homology: human, mouse, rat, canine.

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CITED2 (Cbp/p300-interacting Transactivator 2, MSG-related Protein 1, MRG-1, P35srj, MRG1)

Cat no: C5675-06K

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