CK1 (3C10) Antibody

Cat no: 252668

Supplier: ABBIOTEC

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Description
Additional Information

CK1 (Cytokeratin-1) is an intermediate filament protein. CK1 regulates the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein kinase C (RACK1/GNB2L1). Defects in CK1 are a cause of bullous congenital ichthyosiform erythroderma, also known as epidermolytic hyperkeratosis (EHK) or bullous erythroderma ichthyosiformis congenita of Brocq. BCIE is an autosomal dominant skin disorder characterized by widespread blistering and an ichthyotic erythroderma at birth that persists into adulthood.

Catalogue number:	252668
Reactivities:	Human
Applications:	Immunohistochemistry
Size:	0.1 ml
Accession:	P04264
Antigen:	Purified recombinant fragment of CK1 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	3C10F7, 3C10G5,PorcineMC01, 4D12B3,3C10F7C11
Additional info:	Keratin, type II cytoskeletal 1; 67 kDa cytokeratin; Cytokeratin-1; CK-1; Hair alpha protein; Keratin-1; K1; Type-II keratin Kb1; KRTA; KRT1