Cell-permeable. A highly specific, potent and irreversible proteasome inhibitor. Lactacystin acts as a precursor for clasto-lactacystin beta-lactone and the latter compound is at least 10 times more active than the parent Lactacystin.
Storage and Stability:
Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.