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Cleaved PARP Monoclonal Antibody

Cat no: ABM40145

Cleaved PARP Monoclonal Antibody

PARP1 encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, poly(ADP-ribose) polymerase 1 may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

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SPECIFICATIONS

Catalog Number

ABM40145

Size

30micro l, 100micro l, 200micro l

Applications

IF, IHC-F, WB

Hosts

Mouse

Reactivities

Hum

Gene Id

142

Isotype

Mouse IgG1

Accession

P09874

Clonality

Monoclonal

Concentration

1 mg/ml

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