CLOCK Antibody

Cat no: 252186

Supplier: ABBIOTEC

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Description
Additional Information

CLOCK (Circadian locomoter output cycles protein kaput) heterodimers activate E-bo, Xenopus/Amphibian, element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. CLOCK activates transcription of PER1 and PER2. This transcription is inhibited in a feedback loop by PER and CRY proteins. CLOCK has intrinsic histone acetyltransferase activity and this enzymatic function contributes to chromatin-remodeling events implicated in circadian control of gene e, Xenopus/Amphibian,pression. CLOCK acetylates primarily histones H3 and H4.

Catalogue number:	252186
Reactivities:	Human, Mouse, Rabbit
Applications:	Western Blot
Size:	0.1 mg
Accession:	O15516
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CLOCK.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Circadian locomoter output cycles protein kaput; hCLOCK; Class E basic heli, Xenopus/Amphibian,-loop-heli, Xenopus/Amphibian, protein 8; CLOCK; BHLHE8; KIAA0334