Clock

Cat no: C5843-02A

Supplier: United States Biological

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Clock is a basic helix-loop helix (bHLH) transcription factor that regulates circadian rhythms and sleep cycles. Clock contain a DNA-binding domain, a protein dimerization domain that heterodimerizes with BMAL1 and a glutamine-rich C terminus region. Clock dimerization with BMAL helps regulate nuclear translocation and binding of Clock to the E box elements stimulates circadian genes transcription. Applications: Suitable for use in Western Blot. Other applications have not been tested. Recommended Dilutions: Western Blot: 0.5-4 ug/ml Optimal dilutions to be determined by the researcher. Control Peptide: C5843-02A1 Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Catalogue number:	C5843-02A
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	Western Blot
Size:	100ug
Form:	Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
P type:	Pab
Purity:	Purified by immunoaffinitiy chromatography.
Additional info:	Recognizes the 100kD and the ~62kD isoforms of mouse CLOCK. Species Crossreactivity: human, rat.

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Clock

Cat no: C5843-02A

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