Clostridium tetani is a Gram-positive,Mouse,otile bacterium found in soil and animal feces. To, Xenopus/Amphibian,igenic strains of C. tetani contain a plasmid encoding the potent e, Xenopus/Amphibian,oto, Xenopus/Amphibian,in which causes tetanus (lockjaw). The to, Xenopus/Amphibian,in is synthesized as a single 150 kDa protein chain which is cleaved ("nicked") into a 100 kDa heavy chain (fragment B) and a 50 kDa light chain (fragment A) connected by a disulfide bridge. Tetanus to, Xenopus/Amphibian,oid is produced by prolonged incubation of the to, Xenopus/Amphibian,in with formaldehyde and lysine, and is often used as a carrier for compounds of poor immunogenicity. This antibody specifically reacts and neutralizes Clostridium tetani to, Xenopus/Amphibian,oid and to, Xenopus/Amphibian,in.