CNOT7, Recombinant, Mouse, 1-248aa, His-tag (CCR4-NOT Transcription Complex Subunit 7, CCR4-associated Factor 1, CAF-1, CAF1)

Cat no: C2099-69A

Supplier: United States Biological

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CNOT7, is a ubiquitous transcription factor. It is a component of the CCR4 complex which functions as a general transcription regulation complex. CNOT7 also binds to an anti-proliferative protein, B-cell translocation protein 1 (BTG1), which negatively regulates cell proliferation. Source: Recombinant corresponding to aa1-248 from mouse CNOT7, fused to His-tag at N-terminal expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMPAATVD HSQRICEVWA CNLDEEMKKI RQVIRKYNYV AMDTEFPGVV ARPIGEFRSN ADYQYQLLRC NVDLLKIIQL GLTFMNEQGE YPPGTSTWQF NFKFNLTEDM YAQDSIELLT TSGIQFKKHE EEGIETQYFA ELLMTSGVVL CEGVKWLSFH SGYDFGYLIK ILTNSNLPEE ELDFFEILRL FFPVIYDVKY LMKSCKNLKM FFEDHIDDAK YCGHLYGLGS GSSYVQNGTG NAYEEEASKQ S Molecular Weight: ~31.1kD (MALDI-TOF) Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Catalogue number:	C2099-69A
Size:	100ug
Form:	Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 20% glycerol, 1mM DTT.
Purity:	~80% (SDS-PAGE)
References:	1. Draper M.P., et al. (1995) Mol. Cell. Biol. 15:3487-3495. 2. Bogdan JA, et al. (1998) Biochem J. 336 (Pt 2):471-81

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CNOT7, Recombinant, Mouse, 1-248aa, His-tag (CCR4-NOT Transcription Complex Subunit 7, CCR4-associated Factor 1, CAF-1, CAF1)

Cat no: C2099-69A

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