CNOT8, Recombinant, Human, aa1-292, His-Tag (CCR4-NOT Transcription Complex Subunit 8, CAF1, CALIF, hCAF1, POP2)

Supplier:

United States Biological

Cat no: 137027

CNOT8, Recombinant, Human, aa1-292, His-Tag (CCR4-NOT Transcription Complex Subunit 8, CAF1, CALIF, hCAF1, POP2)

CNOT8 belongs to the CAF1 family. It is a ubiquitous transcription factor required for a diverse set of processes and functions as part of the CCR-NOT complex. The CCR4-NOT complex functions as general transcription regulation complex. This complex contains CHAF1A, CHAF1B, CNOT1, CNOT2, CNOT3, CNOT4, CNOT6 and CNOT8 and binds BTG2. \n\nSource: \nRecombinant protein corresponding to human CNOT8, fused to His-tag at N-terminal expressed in E.coli.\n\nMolecular Weight: \n~35.9kD (315aa) (MALDI-TOF)\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGSMPAALVE NSQVICEVWA SNLEEEMRKI REIVLSYSYI AMDTEFPGVV VRPIGEFRSS IDYQYQLLRC NVDLLKIIQL GLTFTNEKGE YPSGINTWQF NFKFNLTEDM YSQDSIDLLA NSGLQFQKHE EEGIDTLHFA ELLMTSGVVL CDNVKWLSFH SGYDFGYMVK LLTDSRLPEE EHEFFHILNL FFPSIYDVKY LMKSCKNLKG GLQEVADQLD LQRIGRQHQA GSDSLLTGMA FFRMKELFFE DSIDDAKYCG RLYGLGTGVA QKQNEDVDSA QEKMSILAII NNMQQ\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

137027

Size

100ug

Form

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.15M NaCl, 10% glycerol, 1mM DTT.

Purity

~90% (SDS-PAGE)

References

1. Morel A.-P., et al. (2003) J. Cell Sci. 116:2929-2936. 2. Albert T.K., et al. (2000) Nucleic Acids Res. 28:809-817.

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SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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