CNTFR-alpha Antibody

Cat no: 251968

Supplier: ABBIOTEC

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Description
Additional Information

Ciliary neurotrophic factor receptor subunit alpha (CNTFR) is hematopoeitin/interferon-class receptor belonging to the cytokine superfamily of receptors. The encoded gene product represents the CNTF-specific alpha subunit of a heterotrimer forming the CNTF receptor comple, Xenopus/Amphibian,, which also includes LIFR and gp130. CNTFR is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. Signal transduction requires that CNTF bind first to this alpha component, which permits the recruitment of gp130 and LIFR beta to form the tripartite receptor comple, Xenopus/Amphibian,. Signal transduction stimulates gene e, Xenopus/Amphibian,pression, cell survival or differentiation in a variety of neuronal cell types. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified.

Catalogue number:	251968
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 mg
Accession:	P26992
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the venter region of human CNTFR.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.2% BSA with 0.09% sodium azide. Antibody was purified by immunogen-affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Ciliary neurotrophic factor receptor subunit alpha; CNTF receptor subunit alpha; CNTFR-alpha; CNTFR