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COG1 (Component of Oligomeric Golgi Complex 1, CDG2G, LDLB, Conserved Oligomeric Golgi Complex Protein 1, Low Density Lipoprotein Receptor Defect B Complementing)

COG1 (Component of Oligomeric Golgi Complex 1, CDG2G, LDLB, Conserved Oligomeric Golgi Complex Protein 1, Low Density Lipoprotein Receptor Defect B Complementing)

Cat no: C7500-60

Supplier: United States Biological
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The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. It is thought that this protein is required for steps in the normal medial and trans Golgi-associated processing of glycoconjugates and plays a role in the organization of the Golgi-localized complex. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:64000 Western Blot: 0.1-0.3ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human Brain (Cerebellum, Amygdala) lysates Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C7500-60
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris, pH 7.2, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Purity: Purified by affinity chromatography.
Alternative names: DKFZp762L1710, KIAA1381
References: 1. Vasile E, Oka T, Ericsson M, Nakamura N, Krieger M. IntraGolgi distribution of the Conserved Oligomeric Golgi (COG) complex. Exp Cell Res. 2006 Oct 1;312(16):3132-41. PMID: 16857184
Additional info: Recognizes human COG1 at ~100kD.

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