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COL2A1, CT (Collagen alpha-1(II) Chain, Alpha-1 Type II Collagen, Chondrocalcin) (Biotin)

Cat no: C7510-37G-Biotin

COL2A1, CT (Collagen alpha-1(II) Chain, Alpha-1 Type II Collagen, Chondrocalcin) (Biotin)

Alpha-1 chain of type II collagen is a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutant forms of this protein are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia.\n\nApplications: \nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:50-1:100\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

C7510-37G-Biotin

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Conjugates

Biotin

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to Biotin.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

1.Olavarrieta,L., Clin. Genet. 73(3), 262-267 (2008). 2.McAlinden,A., Hum. Mutat. 29(1), 83-90 (2008). 3.Forzano,F., Am. J. Med. Genet. A 143(23), 2815-2820 (2007).

Additional Info

Recognizes human COL2A1.

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