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Collagen I Mouse Monoclonal Antibody(4H10)

Cat no: ABM40379

Collagen I Mouse Monoclonal Antibody(4H10)

COL1A1?collagen type I alpha 1 chain) encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in COL1A1 are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for COL1A1.

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SPECIFICATIONS

Catalog Number

ABM40379

Size

30micro l, 100micro l, 200micro l

Applications

IF, IHC-F

Hosts

Mouse

Reactivities

Hum, Mouse, Rat

Gene Id

1277/1278

Isotype

Mouse IgG1

Accession

P02452

Clonality

Monoclonal

Concentration

1 mg/ml

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