Collagen IV (Collagen Alpha-1(IV) Chain, Collagen IV Alpha 1 Polypeptide, Collagen Of Basement Membrane Alpha 1 Chain, Collagen Type IV Alpha 1, COL4A1, Collagen Alpha-2(IV) Chain, Collagen IV Alpha 2 Polypeptide, Collagen Of Basement Membrane Alpha 2 Cha

Collagen type IV is a major componant of basement membranes, such as those associated with capillaries and within glomeruli. This antibody will help detect col- logen type IV and determine the presence of an intact basal lamina in normal tissues or the loss of structure as seen in various carcinomas.\n\nApplications: \nSuitable for use in Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nImmunohistochemistry: 1:100-1:200 for 1 hr. at RT\nOptimal dilutions to be determined by the researcher.\n\nPositive Control: \nKidney (basement membranes staining pattern)\n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

C7510-53L

Size

1ml

Applications

IHC

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a lyophilized powder in 15mM sodium azide. Reconstitute with 1ml dH2O.

P Type

Mab

Purity

Supernatant

Isotype

IgG1

References

1. Gutterson B A, et al.. Invading squamous cell carcinoma can retain a basal lamina. Laboratory Investigation. 51:82-87 (1984). 2.Hancock W W, et al.. Production of monoclonal antibodies to fibronectin, type IV collagen and other antigens of the human glomerulus. Pathology. 16:197-206 (1984).

Additional Info

Recognizes human Collagen Type IV.

Alternative Names

RP11-90L1.2