Collagen IV (Mouse) Antibody

Cat no: 250485

Supplier: ABBIOTEC

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Description
Additional Information

Type IV collagen is the major structural component of glomerular basement membranes forming a "chicken-wire" meshwork together with laminins,Porcineroteoglycans and entactin/nidogen. There are si, Xenopus/Amphibian, type IV collagen isoforms, alpha 1(IV)-alpha 6(IV), each of which can form a triple heli, Xenopus/Amphibian, structure with 2 other chains to generate type IV collagen network. Defects in type IV collagen are a cause of Alport syndrome autosomal recessive (APSAR), characterized by glomerulonephritis, renal failure, sensorineural deafness and eye abnormalities. Defects in type IV collagen are also a cause of benign familial hematuria (BFH). The antibody is directed against rodent alpha 1 isoform.

Catalogue number:	250485
Reactivities:	Porcine, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q9QZR9
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the center region of mouse type IV collagen (isoform alpha 1).
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Collagen alpha-4(IV) chain; COL4A4