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Collagen Type II (Alpha-1 Type II Collagen, Collagen alpha-1(II) Chain Precursor, Collagen Type II alpha 1 Polypeptide, COL2A1, COL2A1 Protein, Cartilage Collagen, CB11)

Cat no: C7510-37A

Collagen Type II (Alpha-1 Type II Collagen, Collagen alpha-1(II) Chain Precursor, Collagen Type II alpha 1 Polypeptide, COL2A1, COL2A1 Protein, Cartilage Collagen, CB11)

Type II Collagen is the principal collagenous component of cartilage, intervertebral disc and vitreous humour. It is also found in other tissues during development. Its main function is to provide tensile strength and give cartilage the ability to resist shearing forces. Type II Collagen supports chondrocyte adhesion and may influence the differentiated phenotype of these cells. It can also be used as an in vivo model in rats and mice for arthritis studies (injection of Bovine Collagen II induces arthritis). \n\nApplications: \nSuitable for use in ELISA. Other applications not tested.\n\nRecommended Dilutions:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

C7510-37A

Size

100ug

Applications

ELISA

Hosts

Mouse

Reactivities

Bov

Form

Supplied as a liquid in PBS, pH 7.2.

P Type

Mab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG1

Additional Info

Recognizes bovine collagen type II.

Alternative Names

ANFH, AOM, Chondrocalcin, COL11A3, Collagen II alpha 1 (Primary Osteoarthritis Spondyloepiphyseal Dysplasia Congenital), MGC131516, SEDC

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