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Collagen, Type IV, Alpha 6 (COL4A6)

Collagen, Type IV, Alpha 6 (COL4A6)

Cat no: C7510-54K

Supplier: United States Biological
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This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Two splice variants have been identified for this gene. Applications: Suitable for use in ELISA. Other applications have not been tested. Recommended Dilutions: Peptide ELISA Titer: 1:32,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C7510-54K
Reactivities: Human
Hosts: Goat
Applications: ELISA
Size: 100ug
Form: Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by peptide affinity chromatography.
Alternative names: type IV alpha 6 collagen, dJ889N15.4 (Collagen Alpha 6(IV)), collagen of basement membrane, alpha-6, collagen alpha 6 type IV, collagen IV, alpha-6 polypeptide, OTTHUMP00000023835, OTTHUMP00000023834, MGC88184, collagen, type IV, alpha 6, COL4A6
References: 1. Zhang X, Zhou J, Reeders ST, Tryggvason K Structure of the human type IV collagen COL4A6 gene, which is mutated in Alport syndrome-associated leiomyomatosis Genomics. 1996 May 33 (3): 473-9.
Additional info: Recognizes COL4A6. Species sequence homology: human.

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