Complement C1q (Complement Component 1, q Subcomponent) (HRP)

Cat no: C0010-02G

Supplier: United States Biological

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Human C1q is a sub-component of complement C1. C1q associates with complement components C1r and C1s, which are required for the progression of the proteolytic complement cascade. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilutions: ELISA: 1:100-1:400 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	C0010-02G
Reactivities:	Human
Hosts:	Sheep
Applications:	ELISA
Size:	1ml
Form:	Supplied as a liquid in PBS, 0.01% thimerosal, HRP stabilizer. Labeled with horseradish peroxidase (HRP).
P type:	Pab
Isotype:	IgG
Purity:	Purified by Protein G affinity chromatography.
References:	1. Nascimento, E.J. et al. (2009) Alternative complement pathway deregulation is correlated with dengue severity. PLoS One. 4:e6782. 2. Lewis, M.J. et al. (2007) The different effector function capabilities of the seven equine IgG subclasses have implications for vaccine strategies. Mol Immunol. 45: 818-27.
Additional info:	Recognizes human C1q. May react with C1q from other species.

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Complement C1q (Complement Component 1, q Subcomponent) (HRP)

Cat no: C0010-02G

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