C1 component of human complement is a complex of three glycoproteins: C1q, C1r and C1s.
C1q has a molecular weight of 492.000 and is present in plasma in an average concentration of
80 microg/ml. It consists of a complex of 18 polypeptide chains of three different types, A, B and C;
6 of each type. The subcomponent C1q is responsible for the binding of C1q to immuno-
complexes an membranes via the Fc portion of the immunoglobulin.
Applications:
Suitable for use in ELISA, Immunoelectrophoresis and Radial Immunodiffusion. Other applications not tested.
Recommended Dilution:
Optimal dilutions to be determined by the researcher.
Storage and Stability:
Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.