logo
logo
Complement C2, Recombinant, Mouse, 6-His-tag (C3/C5 Convertase, C2, Complement C2b Fragment, Complement C2a Fragment)

Cat no: C7850-09R

Complement C2, Recombinant, Mouse, 6-His-tag (C3/C5 Convertase, C2, Complement C2b Fragment, Complement C2a Fragment)

Complement Component C2 (C2) is a serine protease that is part of the classical pathway of the complement system. The classical complement pathway plays a major role in innate immunity against infection. This pathway is triggered by C1, a multimolecular complex composed of the recognition protein C1q and two serine proteases, C1r and C1s. After proteolytic activation by C1, the single chain form of C2 aa19-760 becomes two chains, which are referred to as C2A and C2B. C2A aa251-760 consists of a vWF domain aa260-457 and a serine protease domain aa480-760. After the activation by C1, C2A combines with complement factor 4B to generate the C3 or C5 convertase. The full length mouse C2 was expressed, and the purified protein consists of a mixture of single chain and C2A form based on the N-terminal sequencing data.\n\nSource:\nRecombinant corresponding to aa1-760 from mouse Complement Component C2, fused to 6-His tag at C-terminal, expressed in mouse myeloma cell line, NS0.\n\nMolecular Weight:\n~58kD, 84kD\n\nBiological Activity:\nMeasured by its ability to cleave a colorimetric peptide substrate, N-carbobenzyloxy- Gly-Arg-ThioBenzyl ester (Z-GR-SBzl), in the presence of 5,5

Prices direct from United States Biological

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

C7850-09R

Size

10ug

Form

Supplied as a liquid in sodium acetate, sodium chloride. BSA free.

Purity

~95% (SDS-PAGE)

References

1. Arlaud, G.J. et al. (2002) Biochem. Soc. Trans. 30:1001.

Read more on Supplier website

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse

More info

Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse

More info

Applications

ELISA

Hosts

Mouse

More info
Advertisehere
BMA Biomedicals Horizontal banner
BMA Biomedicals

Latest promotion FROM:

BMA Biomedicals
View promotion

Latest promotions

Spend less time on DNA cleanup so you can do more science. The MSB Spin PCRapace is the fastest way to purify your DNA from PCR, restriction digestion, and...

New brilliant antibodies, and new lower prices!For flow cytometry reagents in general, \"bright is better.\" The violet-excitable BD Horizon™ BV421 and...

As an incentive to qualify our BSA, we are offering a 20% discount when you purchase your first 100g, 500g or 1000g of any grade of Bovine Serum Albumin....

It is not every day that you are given something for nothing. We are giving away additional spectrophotometer software.Cecil Instruments have enhanced the...

Did your supplier increase the price of Fetal Bovine Serum? Did they substitute the US Origin with USDA? Well say no more! Innovative Research is still...

10% Discount on 2 Rabbit Polyclonal Antibody Service. With over 20 years experience, SDIX has developed into the premier US custom antibody producer,...

We're so sure that you'll prefer Cayman Assay kits over your present brand that we're willing to give you a free assay kit to prove it!

For the past decade scientists have extensively used ATS secondary toxin conjugates to make their own targeted toxins for in vitro use.The ability to combine...

Bulk Cytokines with Custom Vialing.20 - 50% off cytokines, growth factors, chemokines and more...For a limited time Cell Sciences is offering substantial...

Are you planning to have a customised antibody made for your research?Since 2000, Everest has been producing a catalog containing thousands of affinity...

Jenway’s 73 series spectrophotometer range provides four models with a narrow spectral bandwidth of 5nm and an absorbance range of –0.3 to 2.5A,...