Complement C3, Human

Cat no: C7850-10N

Supplier: United States Biological

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Description
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The complement system is an important factor in innate immunity. The complement pathways can be divided in the activation pathways and lytic pathway. The activation pathways lead to the cleavage of the third complement component C3. C3 is cleaved into C3a and C3b, where C3b becomes attached to immune complexes. Futhermore C3b plays a critical role in the amplification loop of the alternative pathway. Applications: Suitable for use in IA, Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Catalogue number:	C7850-10N
Reactivities:	Human
Hosts:	Mouse
Applications:	Immunoprecipitation, Western Blot
Size:	50ug
Form:	0.02% Sodium Azide; 0.1% BSA, PBS
P type:	Mab
Isotype:	IgG2b
Purity:	Purified by Protein G affinity chromatography.
Alternative names:	Complement component 3, ASP, Complement C3 precursor, CPAMD1, Acylation Stimulating Protein Cleavage Product
Additional info:	This antibody reacts with an epitope on C3b and recognizes cleaved C3b and full C3 which plays a central role in the complement system. Species Crossreactivity: Crossreacts with Human.

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Complement C3, Human

Cat no: C7850-10N

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