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Complement C3a (C3 and PZP-like alpha-2-macroglobulin Domain-containing Protein 1, C3, Complement C3 alpha Chain, CPAMD1) (APC)

Cat no: C7850-13L


Supplier: United States Biological
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Complement Component 3a receptor (C3a R) is an ~90kD G protein-coupled 7 transmembrane sulfated glycoprotein expressed on myeloid peripheral blood leukocytes, and on activated lymphocytes, endothelial and internal organ epithelial cells. Engagement of C3a R by C3a activates mast cells and neutrophils, triggering degranulation in airways during asthmatic allergen challenges. It assists in Th2-type inflammatory reactions and stimulates leukocyte chemotaxis. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Hybridoma: Myeloma with B cells from Balb/c mice. Storage and Stability: May be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Freezing Allophycocyanin conjugates will result in a substantial loss of enzymatic activity.
Catalogue number: C7850-13L
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 100 tests
Form: Supplied as a liquid in sodium chloride, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).
P type: Mab
Isotype: IgG2A
Purity: Purified by Protein G affinity chromatography.
Additional info: Recognizes human Complement C3a R.

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