Home  >  Products  >  Complement C3a Receptor (Complement Component 3a Receptor 1, Complement Component 3 Receptor 1, C3AR, C3A-R, C3AR1, AZ3B, C3a Anaphylatoxin Chemotactic Receptor, HNFAG09)
Complement C3a Receptor (Complement Component 3a Receptor 1, Complement Component 3 Receptor 1, C3AR, C3A-R, C3AR1, AZ3B, C3a Anaphylatoxin Chemotactic Receptor, HNFAG09)

Complement C3a Receptor (Complement Component 3a Receptor 1, Complement Component 3 Receptor 1, C3AR, C3A-R, C3AR1, AZ3B, C3a Anaphylatoxin Chemotactic Receptor, HNFAG09)

Cat no: C7850-13T

Supplier: United States Biological
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The receptor for human complement component C3a (C3aR) is a 55kD cell surface protein of the rhodopsin family of G protein-coupled seven-transmembrane receptors. C3a is an anaphylatoxin, which is a potent proinflammatory mediator that possesses immunoregulatory properties. C3a regulates inflammatory functions by binding to the C3a receptor. C3aR is expressed on various tissues and leukocytes including basophils, neutrophils, mast cells, eosinophils and activated T lymphocytes. Expression levels of C3aR on human cells varies significantly between donors. Applications: Suitable for use in Flow Cytometry and Immunohistochemistry (frozen). Other applications not tested. Recommended Dilution: Flow Cytometry: 1:10-1:20; 10ul labels 10e6 cells in 100ul Optimal dilutions to be determined by the researcher. Hybridoma: X63-Ag8.653 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C7850-13T
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry
Size: 200ug
Form: Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein G affinity chromatography.
Additional info: Recognizes the receptor for human complement component C3a (C3aR) at ~55kD.

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