Home  >  Products  >  Complement C5 (Complement Component C5, Anaphylatoxin C5a Analog, C3 and PZP-like alpha-2-macroglobulin Domain-containing Protein 4, CPAMD4)
Complement C5 (Complement Component C5, Anaphylatoxin C5a Analog, C3 and PZP-like alpha-2-macroglobulin Domain-containing Protein 4, CPAMD4)

Complement C5 (Complement Component C5, Anaphylatoxin C5a Analog, C3 and PZP-like alpha-2-macroglobulin Domain-containing Protein 4, CPAMD4)

Cat no: C7850-24R

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
C5 is synthesized in the liver as a single polypeptide chain. Before secretion the molecule is glycosylated and secreted into plasma as a 190kD glycoprotein consisting of disulfide-linked alpha chain (115kD) and beta chain (75kD). It occurs in plasma at about 75mg/ml. C5 is activated, via either the classical or alternative complement pathway, by protoelytic cleavage of C5a (11.5kD) from the N-terminal of the alpha-chain. C5a is a potent anaphylotoxin and stimulates directed migration of neutrophils, eosinophils, basophils and monocytes. The other fragment, C5b, initiates the assembly of the membrane attack complex that mediates the cytolysis of viral and bacterial pathogens. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C7850-24R
Reactivities: Human
Hosts: Goat
Applications: ELISA
Size: 500ug
Form: Supplied as a liquid in 10mM sodium phosphate, 0.15M sodium chloride, pH 7.2, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by affinity chromatography. > 95% by SDS-PAGE.
Additional info: Recognizes human Complement C5.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave