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Compound 401 (2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one)

Compound 401 (2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one)

Cat no: C7849-74

Supplier: United States Biological
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Cell-permeable. A reversible and selective inhibitor of DNA-dependent protein kinase (DNA-PK) (IC?? = 0.28uM) that also targets mTOR (IC50 = 5. 3uM), but not PI 3-K in vitro. Induces apoptosis in vitro. Solubility: DMSO (10mM), EtOH (5mM) Molecular Weight: ~281.31
Catalogue number: C7849-74
Size: 5mg
Form: Supplied as a white to off-white solid.
Purity: ~97% (HPLC)

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