Cell-permeable. A reversible and selective inhibitor of DNA-dependent protein kinase (DNA-PK) (IC?? = 0.28uM) that also targets mTOR (IC50 = 5. 3uM), but not PI 3-K in vitro. Induces apoptosis in vitro.
Solubility:
DMSO (10mM), EtOH (5mM)
Molecular Weight:
~281.31