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Conglobatin

Conglobatin

Cat no: C7852-52

Supplier: United States Biological
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Isolated from Streptomyces conglobatus, conglobatin has a unusual dimeric macrolide dilactone structure with pendant oxazole groups. It exhibited an IC50 of 0.63 ug/ml in a NFAT-dependent transcription assay. No toxicity was observed at doses up to 1000 mg/kg when administered to mice either orally or interperitoneally. Purity: >95% by HPLC Solubility: Soluble in ethanol, methanol, DMF or DMSO. Related to: Elaiophyllin
Catalogue number: C7852-52
Size: 500ug
Purity: >95% by HPLC
References: 1. Simple aromatics identified with a NFAT-lacZ transcription assay for the detection of immunosuppressants. Burres N.E. et al. J. Antibiot. 1995, 48, 380. 2. Conglobatin, a novel macrolide dilactone from Streptomyces conglobatus ATCC 31005. Westley J.W. et al. J. Antibiot. 1979, 32, 874.

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