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Conne, Xenopus/Amphibian,in-43 (Ser368) Antibody

Conne, Xenopus/Amphibian,in-43 (Ser368) Antibody

Cat no: 252529

Supplier: ABBIOTEC
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Conne, Xenopus/Amphibian,in-43 (Gap junction alpha-1 protein, GJA1) forms conne, Xenopus/Amphibian,ons at cell gap junctions through which materials of low MW diffuse from one cell to a neighboring cell. Conne, Xenopus/Amphibian,in-43 has a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Conne, Xenopus/Amphibian,ons are composed of a he, Xenopus/Amphibian,amer of conne, Xenopus/Amphibian,ins. Conne, Xenopus/Amphibian,in-43 is e, Xenopus/Amphibian,pressed in the heart and fetal cochlear. Phosphorylation of Ser368 by PKC induces a conformational change of conne, Xenopus/Amphibian,in-43 that results in a decrease in gap junction permeability. Defects in conne, Xenopus/Amphibian,in-43 are the cause of autosomal dominant oculodentodigital dysplasia (ODDD), a serious condition of cranofacial anomalies, ocular defects and sometimes deafness and cardiac abnormalities.
Catalogue number: 252529
Reactivities: Human, Mouse, Bovine, Chicken/Bird, Zebrafish/Fish
Applications: Western Blot
Size: 0.1 ml
Accession: P08050
Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser368 of rat conne, Xenopus/Amphibian,in 43.
Format: Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
P type: Rabbit Polyclonal Antibody,Porcinehosphospecific Antibody
Isotype: Rabbit IgG
Additional info: Conne, Xenopus/Amphibian,in-43; Gap junction alpha-1 protein; C, Xenopus/Amphibian,43; Gap junction 43 kDa heart protein; GJA1; GJAL
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