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Connexin 32, aa105-123 (GJB1, CX32)

Connexin 32, aa105-123 (GJB1, CX32)

Cat no: C7854-05M

Supplier: United States Biological
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A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexins, through which materials of low molecular weight diffuse from one cell to a neighboring cell. Each connexin is composed of a hexamer of connexin proteins. Connexins are a multi-gene family of highly related proteins. At least a dozen distinct connexin genes have been identified and many are expressed in a tissue-specific manner. Two distinct lineages, class I (beta) and class II (alpha), have been identified in mammals. Connexin 32 belongs to the class 1 group of connexins. Applications: Suitable for use in Immunohistochemistry and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-1.0ug/ml Immunohistochemistry (formalin/acetone fixed tissues): 1-2ug/ml Optimal dilution determined by the researcher. Storage and Stability: Lyophilized powder may be stored at 4 degrees C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C7854-05M
Reactivities: Human, Mouse, Rat
Hosts: Mouse
Applications: Immunohistochemistry, Western Blot
Size: 100ug
Form: Supplied as a lyophilized powder from 1.2% sodium acetate, 2% BSA, 0.2% sodium azide. Reconstitute with sterile PBS to concentration of 0.1-1mg/ml.
P type: Mab
Isotype: IgG
Purity: Purified by affinity chromatography.
Additional info: Recognizes human connexin-32, aa105-123. Species Crossreactivity: mouse, rat. Species sequence homology: chimpanzee, Cynomolgus Monkey, bovine, canine, guinea pig, hamster, chinese hamster, horse and sheep.

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