Catalogue number: |
C7900-50A1 |
Reactivities: |
Human, Rat, Non-Human Primate |
Hosts: |
Mouse |
Applications: |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot |
Size: |
100ul |
Form: |
As reported |
P type: |
Mab |
Isotype: |
IgG1 |
Purity: |
Ascites |
Alternative names: |
Beta-coat protein, betacop, Coatomer beta subunit, Coatomer protein complex subunit beta 1, Coatomer protein complex subunit beta, COPB1, DKFZp761K102, FLJ10341 |
References: |
Kreis TE et al. COPs regulating membrane traffic. Annu Rev Cell Dev Biol 11:677-706 (1995). Griffiths G et al. Immunocytochemical localization of beta-COP to the ER-Golgi boundary and the TGN. J Cell Sci 108 (Pt 8):2839-56 (1995). Whitney JA et al. Cytoplasmic coat proteins involved in endosome function. Cell 83:703-13 (1995). Pepperkok R et al. Beta-COP is essential for biosynthetic membrane transport from the endoplasmic reticulum to the Golgi complex in vivo. Cell 74:71-82 (1993). Oprins A et al. Beta-COP localizes mainly to the cis-Golgi side in exocrine pancreas. J Cell Biol 121:49-59 (1993). Narula N et al. Identification of a 200-kD, brefeldin-sensitive protein on Golgi membranes. J Cell Biol 117:27-38 (1992). Duden R et al. Beta-COP, a 110 kd protein associated with non-clathrin-coated vesicles and the Golgi complex, shows homology to beta-adaptin. Cell 64:649-65 (1991). Ktistakis NT et al. PtK1 cells contain a nondiffusible, dominant factor that makes the Golgi apparatus resistant to brefeldin A. J Cell Biol 113:1009-23 (1991). Donaldson JG et al. Dissociation of a 110-kD peripheral membrane protein from the Golgi apparatus is an early event in brefeldin A action. J Cell Biol 111:2295-306 (1990). Allan VJ & Kreis TE A microtubule-binding protein associated with membranes of the Golgi apparatus. J Cell Biol 103:2229-39 (1986). |
Additional info: |
Recognizes an epitope in the beta-COP protein (110kD). The antibody stains the periphery of the Golgi complex in immunohistology using cultured cells. Species Crossreactivity: Crossreacts with Hamster, Human, Rat and Monkey. |