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COPS3 (M408) Peptide

COPS3 (M408) Peptide

Cat no: BS1192P

Supplier: Bioworld Technology, Inc.
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The COP9 signalosome (CSN) complex is involved in several different developmental and cellular processes. The complex is made up of several widely expressed proteins: CSN1 (COPS1), CSN2 (COPS2), CSN3 (COPS3), CSN4 (COPS4), CSN5 (COPS5), CSN6 (COP6), CSN7a (COPS7, COPS7a) or CSN7b (COP7b) and CSN8 (COP8). The CSN complex acts as a regulator for the ubiquitin conjugation pathway by mediating the deneddylation of the SCF-type E3 ligase complexes, which leads to a decrease in ubiquitin ligase activity of SCF-complexes. It is also involved in the phosphorylation of p53, c-Jun, I?Balpha and IRF-8, as well as CSN-dependent phosphorylation of p53, and c-Jun protects and promotes degradation by the Ubl system.
Catalogue number: BS1192P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q9UNS2
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide COPS3 (M408). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: COP9 signalosome complex subunit 3; SGN3; Signalosome subunit 3; AB1-containing signalosome subunit 3; COPS 3; CSN3
Additional info: This peptide can be used with studies using BS1192 COPS3 (M408) pAb.

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