Cornulin (Tumor Related Protein, C1orf10 Gene Product, Chromosome 1 Open Reading Frame 10 Gene Product)

Cornulin is a survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines. It attenuates deoxycholic acid (DCA)-induced apoptotic cell death and the release of calcium. In overexpressed oral squamous carcinoma cell lines, cornulin negatively regulates cell proliferation by the induction of G1 arrest.\n\nApplications:\nSuitable for use in Immunohistochemistry, Western Blot\n\nRecommended Dilution:\nOptimal dilutions to be determined by researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

044682

Size

50ug

Applications

IHC, WB

Hosts

Rabbit

Form

Supplied as a liquid in PBS, 1% BSA, 0.01% sodium azide.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

References

Product Reference: \n?Cornulin, a new member of the \"fused gene\" family, is expressed during epidermal differentiation: R. Contzler, et al.; J. Invest. Dermatol. 124, 990 (2005)\n?

Additional Info

Recognizes human cornulin. Detects a band of ~70kD by Western blot.

Alternative Names

Tumor Related Protein, C1orf10 Gene Product, Chromosome 1 Open Reading Frame 10 Gene Product