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Coronin 3 (Coronin 1c, Coronin actin binding protein 1C, HCRNN4)

Coronin 3 (Coronin 1c, Coronin actin binding protein 1C, HCRNN4)

Cat no: C7901-38A

Supplier: United States Biological
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Coronin 3 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD). These may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. By similarity, Coronin 3 may be involved in cytokinesis, motility, and signal transduction. Coronin 3 is ubiquitously expressed in all human tissues, in contrast to other known coronin-like molecules, each of which is expressed in a tissue-specific manner. Positive Control: Human lung and placenta lysates Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C7901-38A
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Tris saline, 0.02% Na azide, (pH 7.3) with 0.5% BSA
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: Coronin 1c, Coronin actin binding protein 1C, HCRNN4
References: Iizaka M et al. Isolation and chromosomal assignment of a novel human gene, CORO1C, homologous to coronin-like actin-binding proteins. Cytogenet Cell Genet 88:221-4 (2000).
Additional info: Species Crossreactivity: Crossreacts with Human. Expected to crossreact with Mouse (85% identity with immunogen) due to sequence homology.

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