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Products COX 2 (Cyclooxygenase 2, PGHS 2, Prostaglandin Endoperoxide Synthase 2, PHS 2) (FITC)
| Catalogue number: | C7904-82K |
| Reactivities: | Human, Sheep |
| Hosts: | Mouse |
| Applications: | Flow Cytometry, Immunocytochemistry |
| Size: | 100ug |
| Form: | Supplied as a liquid in PBS, pH 7.2, 4mg/ml BSA, 0.02% sodium azide, 50% glycerol. Labeled with fluorescein isothiocyanate (FITC). |
| P type: | Mab |
| Isotype: | IgG1 |
| Purity: | Purified |
| References: | 1.Hla, T., Neilson, K.. Human cyclooxygenase-2 cDNA. Proc Natl Acad Sci USA 89 7384-7388 (1992).2. Xie, W., Chipman, J.G., Robertson, D.L., et al. Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc Natl Acad Sci USA 88 2692-2696 (1991).3. Kujubu, D.A., Fletcher, B.S., Varnum, B.C., et al. TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue. J Biol Chem 266 12866-12872 (1991).4. Yamagata, K., Andreasson, K.I., Kaufmann, W.E., et al. Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids. Neuron 11 371-386 (1993).5. Zhang, V., O'Sullivan, M., Hussain, H., et al. Molecular cloning, functional expression, and selective regulation of ovine prostaglandin H synthase-2. Biochem Biophys Res Commun 227 499-506 (1996).6. Litherland, S.A., Xie, X.T., Hutson, A.D., et al. Aberrant prostaglandin synthase 2 expression defines an antigen-presenting cell defect for insulin-dependent diabetes mellitus. J Clin Invest 104 515-523 (1999). |
| Additional info: | Recognizes human COX-2. Species crossreactivity: sheep. Does not cross-react with mouse, rat, and rabbit COX-2 or COX-1 (all species). |
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