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COX 4-1 (COX IV-1)

COX 4-1 (COX IV-1)

Cat no: C7904-89C

Supplier: United States Biological
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Cytochrome C Oxidase (COX), which is located in the inner mitochondrial membrane, is the terminal enzyme complex of the mitochondrial electron transport chain. It collects electrons that are transferred from reduced Cytochrome C and donates them to molecular oxygen, which is then reduced to water. Antibodies to this protein make an effective loading control for mitochondria. COXIV (COX4 )is generally expressed at a consistently high level. However, be aware that many proteins run at the same molecular weight as COXIV. Some caution is required when using antibodies to this protein as a loading control, as COXIV expression can vary under some manipulations. Cellular Localization: Mitochondrion, mito inner membrane Positive Control: HEK 293 lysates, Hela lysates Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C7904-89C
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 100ul
Form: Supplied as a liquid in Tris-glycine, 150mM sodium chloride, pH 7.2.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Alternative names: Cytochrome C oxidase subunit IV isoform 1, mitochondrial EC=1.9.3.1, COX IV-1, Cytochrome C oxidase polypeptide IV, COX4l1, COX4, cox 4-1, COX4-1
Additional info: This antibody is specific for COX41. Species Crossreactivity: This antibody reacts with the human COX41 protein.

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