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CpG-B DNA, Human, Mouse, K-type, BioGenomics(TM)

Cat no: C7905-82


Supplier: United States Biological
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ODN 2006 is a prototype of the class of CpG-B oligodeoxynucleotides (ODN), also known as
Catalogue number: C7905-82
Applications: ELISA
Size: 200nmol
Form: Supplied as a lyophilized powder. Endotoxin levels are undetectable. Reconstitute with sterile ddH2O.
Purity: Purified
References: 1. Krieg, A; CpG motifs in bacterial DNA and their immune effects. Annu Rev Immunol 2002, 20: 709 2. Vollmer, J et al; Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities. Eur J Immunol 2004, 34: 251 3. Kerkmann, M et al; Activation with CpG-A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells. J Immunol 2003,170: 4465 4. Wang, J et al; CpG-independent synergistic induction of beta-chemokines and a dendritic cell phenotype by orthophosphorothioate ODN and GM-CSF in elutriated human primary monocytes. J Immunol 2005, 174: 6113 5. Latz, E et al; TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nat Immunol 2004, 5: 190 .

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