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CPT1B (isoform 1) Carnitine Palmitoyltransferase 1B (muscle)

CPT1B (isoform 1) Carnitine Palmitoyltransferase 1B (muscle)

Cat no: C7906-06B3

Supplier: United States Biological
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The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications have not been tested. Recommended Dilutions: Peptide ELISA Titer: 1:16,000 Immunohistochemistry: 3-5ug/ml; In paraffin embedded Human Heart shows staining of myocardial fibres in longitudinal section. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C7906-06B3
Reactivities: Human
Hosts: Goat
Applications: ELISA, Immunohistochemistry
Size: 100ug
Form: Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by peptide affinity chromatography.
Alternative names: carnitine palmitoyltransferase I-like, MCPT1, MCCPT1, FLJ58750, FLJ55729, CPT1M, carnitine palmitoyltransferase 1B (muscle), carnitine palmitoyltransferase 1B, carnitine palmitoyltransferase 1A (muscle), carnitine O-palmitoyltransferase I, mitochondrial muscle isoform, CPTI, muscle, KIAA1670, M-CPT1, CPT1-M, carnitine palmitoyltransferase 1B (muscle), carnitine palmitoyltransferase I, muscle, CPT1B
References: 1.Yamazaki N, Shinohara Y, Shima A, Yamanaka Y, Terada H. Isolation and characterization of cDNA and genomic clones encoding human muscle type carnitine palmitoyltransferase I.Biochim Biophys Acta. 1996 Jun 7;1307(2):157-61.
Additional info: Recognizes human CPT1B. This antibody is expected to recognise human isoforms a (NP_689452.1; NP_689451.1; NP_004368.1; NP_001138609.1; NP_001138607.1), isoform c (NP_001138606.1) and isoform d (NP_001138608.1).

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