CPT1B (isoform 1) Carnitine Palmitoyltransferase 1B (muscle)

The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene.\n\nApplications:\nSuitable for use in ELISA and Immunohistochemistry. Other applications have not been tested. \n\nRecommended Dilutions: \nPeptide ELISA Titer: 1:16,000\nImmunohistochemistry: 3-5ug/ml; In paraffin embedded Human Heart shows staining of myocardial fibres in longitudinal section. \nOptimal dilutions to be determined by the researcher. \n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

C7906-06B3

Size

100ug

Applications

ELISA, IHC

Hosts

Goat

Reactivities

Hum

Form

Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.

P Type

Pab

Purity

Purified by peptide affinity chromatography.

Isotype

IgG

References

1.Yamazaki N, Shinohara Y, Shima A, Yamanaka Y, Terada H. Isolation and characterization of cDNA and genomic clones encoding human muscle type carnitine palmitoyltransferase I.Biochim Biophys Acta. 1996 Jun 7;1307(2):157-61.

Additional Info

Recognizes human CPT1B. This antibody is expected to recognise human isoforms a (NP_689452.1; NP_689451.1; NP_004368.1; NP_001138609.1; NP_001138607.1), isoform c (NP_001138606.1) and isoform d (NP_001138608.1).

Alternative Names

carnitine palmitoyltransferase I-like, MCPT1, MCCPT1, FLJ58750, FLJ55729, CPT1M, carnitine palmitoyltransferase 1B (muscle), carnitine palmitoyltransferase 1B, carnitine palmitoyltransferase 1A (muscle), carnitine O-palmitoyltransferase I, mitochondrial muscle isoform, CPTI, muscle, KIAA1670, M-CPT1, CPT1-M, carnitine palmitoyltransferase 1B (muscle), carnitine palmitoyltransferase I, muscle, CPT1B