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CRABP2 (Cellular Retinoic Acid-binding Protein 2, Cellular Retinoic Acid-binding Protein II, CRABP-II)

CRABP2 (Cellular Retinoic Acid-binding Protein 2, Cellular Retinoic Acid-binding Protein II, CRABP-II)

Cat no: C7906-71G

Supplier: United States Biological
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Cellular retinoic acid binding protein (CRABP) is a low molecular weight protein with unknown function and existing in two isoforms, CRABP1 and CRABP2. The predicted aa sequences of human CRABP1 and CRABP2 exhibits 99.3 and 93.5% identity to mouse CRABP1 and CRABP2, respectively. The CRABP2 isoform is important in retinoic acid-mediated regulation of human skin growth and differentiation. The CRABP2 gene localized on human chromosome 1q21.3 is transcriptionally regulated by a newly synthesized regulatory protein. The protein is expressed in human adult liver. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.5-2ug/ml Immunohistochemistry (formalin fixed paraffin embedded): 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C7906-71G
Reactivities: Human, Mouse, Non-Human Primate
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by Protein G affinity chromatography.
References: 1. Astrom, A. et al. J. Biol. Chem. 266:17662-17662 (1991). 2. Wang, L. et al. Biochemistry. 37:12727-36 (1998).
Additional info: Recognizes human CRABP2. Species Crossreactivity: monkey. Species sequence homology: mouse, rat, bovine, canine.

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