CREB-1 Antibody

Cat no: 250613

Supplier: ABBIOTEC

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Description
Additional Information

As a dimer, CREB-1 (cAMP-responsive element-binding protein 1) binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters, to stimulate transcription. CREB-1 is activated by phosphorylayion on Ser-133 and Ser-142. Transcriptional activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. CREB-1 has been implicated in synchronization of circadian rhythmicity. It interacts with various proteins including TORC/CRTC, CREBBP, ARRB1.

Catalogue number:	250613
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P16220
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CREB-1.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Mouse Polyclonal Antibody
Isotype:	Rabbit IgG
Additional info:	Cyclic AMP-responsive element-binding protein 1; cAMP response element-binding protein; CREB; CREB1; CREB-1