CREB-1 Antibody

Cat no: 252116

Supplier: ABBIOTEC

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Description
Additional Information

Cyclic AMP-responsive element-binding protein 1 (CREB-1) is a protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB-1 stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. CREB-1 is implicated in synchronization of circadian rhythmicity. Defects in CREB-1 have been implicated in angiomatoid fibrous histiocytoma (AFH), a distinct variant of malignant fibrous histiocytoma that typically occurs in children and adolescents and is manifest by nodular subcutaneous growth.

Catalogue number:	252116
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P16220
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CREB-1.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Cyclic AMP-responsive element-binding protein 1; cAMP-responsive element-binding protein 1; CREB-1; CREB1